ExoticRx · exoticrx.com/drugs/estradiol
US brand names:ECP(Estradiol Cypionate), Depo-Estradiol
Also known as: Oestradiol
Estradiol is dosed at 0.02 mg/kg IM once q14-28 days in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Natural estrogen binding estrogen receptors. Stimulates reproductive tract and secondary sex characteristics. Dose-dependent bone marrow effects.
APLASTIC ANEMIA at misbreeding-prevention doses — potentially fatal. Dogs extremely sensitive. Never use for mismating prevention. Bone marrow suppression is dose-dependent and irreversible.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 0.02 mg/kg | once q14-28 days | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.