ExoticRx · exoticrx.com/drugs/ethosuximide
US brand names:Zarontin
Reduces low-threshold T-type calcium currents in thalamic neurons, suppressing the thalamocortical spike-wave discharge underlying absence seizures.
Specific for absence seizures only — not effective for generalized tonic-clonic seizures. GI upset common. Blood dyscrasias rare. Very limited veterinary use.
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