Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Fluoxetine is dosed at 5–10 mg/kg PO q24h in guinea pigs, per Jepson L. Exotic Animal Medicine: A Quick Reference Guide, WB Saunders, New York, NY; 2009. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.800 (2026-08-01, PENDING REVIEW). Fluoxetine is used in guinea pigs for Behavioral problems (e.g., fur chewing). Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Fluoxetine in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Reconcile, Prozac
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q24h | Behavioral problems (e.g., fur chewing) | Weak | Jepson L. Exotic Animal Medicine: A Quick Reference Guide, WB Saunders, New York, NY; 2009. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.800 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selectively inhibits serotonin reuptake at the presynaptic membrane, increasing serotonergic neurotransmission.
Reconcile FDA-approved for canine separation anxiety. 4-6 weeks for full effect. Serotonin syndrome risk with tramadol, MAOIs, TCAs. Reduced appetite, lethargy initially. Long half-life.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fluoxetine dose range in guinea pigs, with cited source references: PO 5–10 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fluoxetine in guinea pigs: PO.
Fluoxetine is indicated in guinea pigs for: Behavioral problems (e.g., fur chewing).
These are general warnings for Fluoxetine across species; consult the guinea pig dosing table above for species-specific guidance. Reconcile FDA-approved for canine separation anxiety. 4-6 weeks for full effect. Serotonin syndrome risk with tramadol, MAOIs, TCAs. Reduced appetite, lethargy initially. Long half-life.
Why a species-specific page? Fluoxetine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.