Cat · Felis catus · typical adult weight 2.50–7.00 kg
Frunevetmab is dosed at 7–14 mg/cat (NOT mg/kg) - whole vials SC q4 weeks (monthly) in cats, per SOLENSIA - Frunevetmab Injection [US Product Label for Cats]. Zoetis Inc.; 2022. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a73b79c4-3623-4b52-81ea-6180528a031e — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.589 (2026-08-01). — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as mg/kg, which the calculator multiplies by body weight and can yield a fractional vial - a dose that does not exist as a product. Plumb's 10th ed, Frunevetmab monograph, corpus p.589, label dosage (FDA approved), verbatim: "Cats weighing 2.5 to 7 kg (5.5 to 15.4 lb): 1 vial (7 mg, 1 mL)/cat (NOT mg/kg) SC once per month […]" Corpus p.589 also records the product as "Frunevetmab Injection: 7 mg/mL in 1 mL single-use vials ... Solensia (Rx). NADA #141-546". Read from the page 2026-08-13.. Frunevetmab is used in cats for Osteoarthritis pain, Osteoarthritis pain (FDA-approved). Routes documented in cats: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 2 cited dose rules for Frunevetmab in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Solensia, Solensia (Frunevetmab Solution)
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 7–14 mg/cat (NOT mg/kg) - whole vials | q4 weeks (monthly) | Long-term monthly injections | Osteoarthritis pain | Strong | SOLENSIA - Frunevetmab Injection [US Product Label for Cats]. Zoetis Inc.; 2022. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a73b79c4-3623-4b52-81ea-6180528a031e — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.589 (2026-08-01). — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as mg/kg, which the calculator multiplies by body weight and can yield a fractional vial - a dose that does not exist as a product. Plumb's 10th ed, Frunevetmab monograph, corpus p.589, label dosage (FDA approved), verbatim: "Cats weighing 2.5 to 7 kg (5.5 to 15.4 lb): 1 vial (7 mg, 1 mL)/cat (NOT mg/kg) SC once per month […]" Corpus p.589 also records the product as "Frunevetmab Injection: 7 mg/mL in 1 mL single-use vials ... Solensia (Rx). NADA #141-546". Read from the page 2026-08-13. |
| SC | 7–14 mg/cat (NOT mg/kg): 1 vial (7 mg) or 2 vials (14 mg) | SC once monthly, by weight band | Monthly, long-term | Osteoarthritis pain (FDA-approved) | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Frunevetmab monograph, printed p.561; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, |
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Felinized anti-nerve growth factor (NGF) monoclonal antibody. Binds and neutralizes NGF preventing pain signaling in osteoarthritis.
FDA-approved for OA pain in cats. Monthly SC injection. Very well tolerated. Injection site reactions rare. Not for use in breeding cats. Novel biologic approach.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frunevetmab dose ranges in cats, with cited source references: SC 7–14 mg/cat (NOT mg/kg) - whole vials q4 weeks (monthly); SC 7–14 mg/cat (NOT mg/kg): 1 vial (7 mg) or 2 vials (14 mg) SC once monthly, by weight band. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Frunevetmab in cats: SC.
Cited course lengths for Frunevetmab in cats include: Long-term monthly injections; Monthly, long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Frunevetmab is indicated in cats for: Osteoarthritis pain, Osteoarthritis pain (FDA-approved).
These are general warnings for Frunevetmab across species; consult the cat dosing table above for species-specific guidance. FDA-approved for OA pain in cats. Monthly SC injection. Very well tolerated. Injection site reactions rare. Not for use in breeding cats. Novel biologic approach.
Why a species-specific page? Frunevetmab pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.