ExoticRx · exoticrx.com/drugs/frunevetmab
US brand names:Solensia, Solensia (Frunevetmab Solution)
Frunevetmab is dosed at 7–14 mg/cat (NOT mg/kg): 1 vial (7 mg) or 2 vials (14 mg) SC SC once monthly, by weight band in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Frunevetmab monograph, printed p.561; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Felinized anti-nerve growth factor (NGF) monoclonal antibody. Binds and neutralizes NGF preventing pain signaling in osteoarthritis.
FDA-approved for OA pain in cats. Monthly SC injection. Very well tolerated. Injection site reactions rare. Not for use in breeding cats. Novel biologic approach.
Species references:All Cat (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | SC | 7–14 mg/cat (NOT mg/kg): 1 vial (7 mg) or 2 vials (14 mg) | SC once monthly, by weight band | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Frunevetmab monograph, printed p.561; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | SC | 7–14 mg/cat (NOT mg/kg) - whole vials | q4 weeks (monthly) | Strong | SOLENSIA - Frunevetmab Injection [US Product Label for Cats]. Zoetis Inc.; 2022. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.589 (2026-08-01). — Plumb's 10th ed (held) printed p.561, Frunevetmab monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, BASIS CORRECTED 2026-08-13: served as mg/kg, which the calculator multiplies by body weight and can yield a fractional vial - a dose that does not exist as a product. Plumb's 10th ed, Frunevetmab monograph, corpus p.589, label dosage (FDA approved), verbatim: "Cats weighing 2.5 to 7 kg (5.5 to 15.4 lb): 1 vial (7 mg, 1 mL)/cat (NOT mg/kg) SC once per month […]" Corpus p.589 also records the product as "Frunevetmab Injection: 7 mg/mL in 1 mL single-use vials ... Solensia (Rx). NADA #141-546". Read from the page 2026-08-13. |
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