ExoticRx · exoticrx.com/drugs/etidronate
US brand names:Didronel
Etidronate is dosed at 5 mg/kg PO q24h in dogs, per Papich, Saunders Handbook of Veterinary Drugs, 4th Ed (2016), p.334 — Etidronate Disodium, Small Animal Dosage, Dogs.. Verify against current literature before clinical use.
First-generation bisphosphonate inhibiting osteoclast-mediated bone resorption. Adsorbs to hydroxyapatite crystal surface.
Can impair bone mineralization at high doses (unlike newer bisphosphonates). Give on empty stomach. Esophageal irritation. Limited veterinary use — newer bisphosphonates preferred.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5 mg/kg | q24h | Weak | Papich, Saunders Handbook of Veterinary Drugs, 4th Ed (2016), p.334 — Etidronate Disodium, Small Animal Dosage, Dogs. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.