ExoticRx · exoticrx.com/drugs/hyaluronic-acid
Hyaluronic Acid
Legend, Hyalovet
Drug Class
Routes
Indications
Mechanism of Action
Natural GAG component of synovial fluid and cartilage matrix. Restores viscoelastic properties of synovial fluid. Anti-inflammatory and analgesic effects.
Side effects & warnings
FDA-approved (Legend) for equine joint disease (IV or IA). Used in dogs IA. Transient joint effusion after IA injection. Very safe. Aseptic technique essential for IA route.
Species with Hyaluronic Acid dosing data (1 dose rule)
Species references:All Dog (Domestic) drugs
Evidence levels across 1 dose rule
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published source
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (1 of 1 cited rule)
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Intra-articular | 0 mg/kg | Single injection per joint | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.