ExoticRx · exoticrx.com/drugs/hydrocortisone-aceponate
US brand names:Cortavance
Hydrocortisone Aceponate is dosed at 1.52 mcg/cm2 Topical q24h in dogs, per Bonneau S, Skowronski V and Maynard L (2006) Efficacy of a 0.0584% hydrocortisone aceponate spray in the treatment of pruritic inflammatory skin disease in dogs. Veterinary Dermatology 17, 354-355 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.214 (2026-08-01).. Verify against current literature before clinical use.
Diester topical corticosteroid designed for high local potency with minimal systemic absorption. Metabolized in the skin to active metabolite, providing targeted anti-inflammatory effects.
Avoid on open wounds. Skin atrophy with prolonged use. Minimal systemic effects compared to other topical steroids. Approved for dogs in Europe; available off-label in other markets.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Topical | 1.52 mcg/cm2 | q24h | Strong | Bonneau S, Skowronski V and Maynard L (2006) Efficacy of a 0.0584% hydrocortisone aceponate spray in the treatment of pruritic inflammatory skin disease in dogs. Veterinary Dermatology 17, 354-355 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.214 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.