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Hydrocortisone Oral for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Hydrocortisone Oral is used in cat for Hypoadrenocorticism (glucocorticoid replacement). Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Hydrocortisone Oral in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Cortef

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.5–1 mg/kgq12hLifelong; feline Addison's is very rareHypoadrenocorticism (glucocorticoid replacement)WeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Identical to endogenous cortisol. Binds glucocorticoid and mineralocorticoid receptors, providing physiologic replacement in adrenal insufficiency.

Side effects & warnings

Shortest-acting oral corticosteroid — may need 2-3 daily doses. Used for Addison's disease replacement. Both gluco- and mineralocorticoid effects.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with cat dosing

Hydrocortisone Oral dosing in other species

Why a species-specific page? Hydrocortisone Oral pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.