Cat · Felis catus · typical adult weight 2.50–7.00 kg
Imipenem-Cilastatin is used in cat for Multi-drug resistant infections. Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Imipenem-Cilastatin in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Primaxin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q6-8h | 7-14 days | Multi-drug resistant infections | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Binds penicillin-binding proteins, inhibiting cell wall synthesis. Ultra-broad spectrum including many resistant organisms. Cilastatin prevents renal metabolism of imipenem.
Reserve for multi-drug resistant infections. May lower seizure threshold. Nausea and vomiting with rapid IV infusion. Administer IV slowly over 20-30 minutes.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Imipenem-Cilastatin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.