ExoticRx · exoticrx.com/drugs/isoflupredone
US brand names:Predef 2X
Isoflupredone is dosed at 0.02–0.1 mg/kg IM q24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database. Verify against current literature before clinical use.
Potent fluorinated glucocorticoid that suppresses inflammation by inhibiting phospholipase A2, reducing prostaglandin and leukotriene synthesis, and modulating immune cell function.
Mineralocorticoid effects can cause hypokalemia — supplement potassium if used repeatedly. Immunosuppression risk. Avoid in pregnant animals. Primarily used in cattle and horses.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 0.02–0.1 mg/kg | q24h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.