Cat · Felis catus · typical adult weight 2.50–7.00 kg
Isosorbide Dinitrate is dosed at 0.5–1 mg/kg PO q12h in cats, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.443 (2026-08-01).. Isosorbide Dinitrate is used in cats for Heart failure (preload reduction). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Isosorbide Dinitrate in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Isordil, Dilatrate
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q12h | Short-term use preferred; limited feline data | Heart failure (preload reduction) | Extrapolated | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.443 (2026-08-01). |
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Organic nitrate that releases nitric oxide, causing venodilation primarily and some arteriolar dilation, reducing preload and myocardial oxygen demand.
Tolerance develops with continuous use — nitrate-free interval recommended. Hypotension risk. Headache common.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Isosorbide Dinitrate dose range in cats, with cited source references: PO 0.5–1 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Isosorbide Dinitrate in cats: PO.
Cited course lengths for Isosorbide Dinitrate in cats include: Short-term use preferred; limited feline data. Duration depends on the indication — match it to the specific dose rule in the table above.
Isosorbide Dinitrate is indicated in cats for: Heart failure (preload reduction).
These are general warnings for Isosorbide Dinitrate across species; consult the cat dosing table above for species-specific guidance. Tolerance develops with continuous use — nitrate-free interval recommended. Hypotension risk. Headache common.
Why a species-specific page? Isosorbide Dinitrate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.