ExoticRx · exoticrx.com/drugs/isosorbide-dinitrate
US brand names:Isordil, Dilatrate
Isosorbide Dinitrate is dosed at 0.22–1.1 mg/kg PO q12h in cats, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.443 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.443' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.415; verified by finding the drug named there. If you are holding the book, turn to p.415. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Verify against current literature before clinical use.
Organic nitrate that releases nitric oxide, causing venodilation primarily and some arteriolar dilation, reducing preload and myocardial oxygen demand.
Tolerance develops with continuous use — nitrate-free interval recommended. Hypotension risk. Headache common.
Species references:All Cat (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 0.22–1.1 mg/kg | q12h | Extrapolated | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.443 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.443' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.415; verified by finding the drug named there. If you are holding the book, turn to p.415. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
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