ExoticRx · exoticrx.com/drugs/isosorbide-dinitrate
US brand names:Isordil, Dilatrate
Isosorbide Dinitrate is dosed at 0.22–1.1 mg/kg PO q12h in cats, per Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.415. Verify against current literature before clinical use.
Organic nitrate that releases nitric oxide, causing venodilation primarily and some arteriolar dilation, reducing preload and myocardial oxygen demand.
Tolerance develops with continuous use — nitrate-free interval recommended. Hypotension risk. Headache common.
Species references:All Cat (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 0.22–1.1 mg/kg | q12h | Extrapolated | Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.415Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.