Reptile · Eublepharis macularius · typical adult weight 0.04–0.10 kg
Levothyroxine is dosed at 0.02 mg/kg PO q48h in leopard geckos, per Hadfield CA, Clayton LA, Clancy MM. Proliferative thyroid lesions in three diplodactylid geckos: Nephrurus amyae, Nephrurus levis, and Oedura marmorata. J Zoo Wildl Med. 2012,43:131-140. - Carpenter's Exotic Animal Formulary 6th ed, Table 4.8 (Hormones and Steroids Used in Reptiles): 'Levothyroxine | 0.02 mg/kg PO q48h172 | Geckos/post thyroidectomy, lifetime management'. SOURCE EDITION: Carpenter's Exotic Animal Formulary - ISBN 9780323833929. The entry 'Clinical Guide to Fish Medicine - ISBN 9781119259558' is REMOVED - no fish text bears on a gecko thyroid row.. Levothyroxine is used in leopard geckos for Post-thyroidectomy hormone replacement. Routes documented in leopard geckos: PO. A typical adult leopard gecko weighs 0.04–0.10 kg. ExoticRx lists 1 cited dose rule for Levothyroxine in leopard geckos, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Soloxine, Thyro-Tabs
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 0.02 mg/kg | q48h | Post-thyroidectomy hormone replacement | Weak | Hadfield CA, Clayton LA, Clancy MM. Proliferative thyroid lesions in three diplodactylid geckos: Nephrurus amyae, Nephrurus levis, and Oedura marmorata. J Zoo Wildl Med. 2012,43:131-140. - Carpenter's Exotic Animal Formulary 6th ed, Table 4.8 (Hormones and Steroids Used in Reptiles): 'Levothyroxine | 0.02 mg/kg PO q48h172 | Geckos/post thyroidectomy, lifetime management'. SOURCE EDITION: Carpenter's Exotic Animal Formulary - ISBN 9780323833929. The entry 'Clinical Guide to Fish Medicine - ISBN 9781119259558' is REMOVED - no fish text bears on a gecko thyroid row. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.02 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.8 | 0.02 mg/kg PO q48h |
| 0.02 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.6 | 0.02 mg/kg PO q48h112 Geckos/postthyroidectomy, lifetime management |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your leopard gecko's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic T4 (thyroxine) that is converted to active T3 in peripheral tissues. Restores normal metabolic rate, thermogenesis, and organ function.
Dose based on body weight, adjusted by monitoring serum T4 levels (4-6 hour post-pill sample). Give on empty stomach. Monitor for signs of thyrotoxicosis (tachycardia, panting, anxiety). Dogs primarily.
Species-specific contraindications and adverse-reaction reports for leopard geckos may differ from canine / feline reference data — consult the primary citations listed with each rule.
Levothyroxine dose range in leopard geckos, with cited source references: PO 0.02 mg/kg q48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Levothyroxine in leopard geckos: PO.
Levothyroxine is indicated in leopard geckos for: Post-thyroidectomy hormone replacement.
These are general warnings for Levothyroxine across species; consult the leopard gecko dosing table above for species-specific guidance. Dose based on body weight, adjusted by monitoring serum T4 levels (4-6 hour post-pill sample). Give on empty stomach. Monitor for signs of thyrotoxicosis (tachycardia, panting, anxiety). Dogs primarily.
Why a species-specific page? Levothyroxine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in leopard geckos — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.