ExoticRx · exoticrx.com/drugs/lokivetmab-injectable
US brand names:Cytopoint Injectable, Cytopoint
Lokivetmab Injectable is dosed at 1–2 mg/kg SC q4-8 weeks in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed — Lokivetmab, Dosages: DOGS, label dosage (corpus p.799); 1 mg/kg lower bound from the extra-label entry on corpus p.800. Verify against current literature before clinical use.
Caninized monoclonal antibody targeting interleukin-31 (IL-31), a key pruritogenic cytokine. Neutralizes IL-31 before it can bind to its receptor on sensory neurons.
Dogs only (species-specific). Vomiting may occur post-injection. Avoid in breeding/pregnant/lactating dogs. Efficacy lasts ~4-8 weeks. No known drug interactions.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 1–2 mg/kg | q4-8 weeks | Strong | Plumb's Veterinary Drug Handbook, 9th Ed — Lokivetmab, Dosages: DOGS, label dosage (corpus p.799); 1 mg/kg lower bound from the extra-label entry on corpus p.800 |
| Dog (Domestic) | SC | 1–2 mg/kg | q4-8 weeks | Strong | Plumb's Veterinary Drug Handbook, 9th Ed — Lokivetmab, Dosages: DOGS, label dosage (corpus p.799); 1 mg/kg lower bound from the extra-label entry on corpus p.800 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.