ExoticRx · exoticrx.com/drugs/metformin
Glucophage
Reduces hepatic glucose output, increases insulin sensitivity, and decreases intestinal glucose absorption. Does not cause hypoglycemia as monotherapy.
Limited veterinary use. Lactic acidosis risk (rare). GI upset common. Contraindicated in renal/hepatic insufficiency. Not a first-line in veterinary diabetes.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–10 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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