ExoticRx · exoticrx.com/drugs/metformin
US brand names:Glucophage
Metformin is dosed at 5–10 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Reduces hepatic glucose output, increases insulin sensitivity, and decreases intestinal glucose absorption. Does not cause hypoglycemia as monotherapy.
Limited veterinary use. Lactic acidosis risk (rare). GI upset common. Contraindicated in renal/hepatic insufficiency. Not a first-line in veterinary diabetes.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–10 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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