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Miconazole-Chlorhexidine Shampoo

Malaseb

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Dermatologic

Routes

Topical

Indications

Dermatophytosis adjunctMixed bacterial-fungal skin infection

Mechanism of Action

Dual-action: miconazole disrupts fungal cell membranes via ergosterol inhibition; chlorhexidine provides broad-spectrum antibacterial activity via cell membrane disruption.

Side effects & warnings

Gold standard for concurrent Malassezia and bacterial skin infections. Leave on 10 minutes. Twice weekly initially, then weekly maintenance. Safe for dogs and cats.

Species with Miconazole-Chlorhexidine Shampoo dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Miller WH, Small Animal Dermatology, 7th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Topical0 mg/kgBathe 2x weekly; 10-min contact timeStrongMiller WH, Small Animal Dermatology, 7th Ed
Cat (Domestic)Topical0 mg/kgBathe 2x weekly; 10-min contact timeModerateMiller WH, Small Animal Dermatology, 7th Ed

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Calculate Dosage for Miconazole-Chlorhexidine Shampoo