What is Miconazole-Chlorhexidine Shampoo used for?

Miconazole-Chlorhexidine Shampoo is indicated for: Dermatophytosis adjunct, Mixed bacterial-fungal skin infection.

Which species have cited Miconazole-Chlorhexidine Shampoo dosing data?

Miconazole-Chlorhexidine Shampoo dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Is Miconazole-Chlorhexidine Shampoo a controlled substance?

Miconazole-Chlorhexidine Shampoo is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Miconazole-Chlorhexidine Shampoo

US brand names:Malaseb

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Dermatologic

Routes

Topical

Indications

Dermatophytosis adjunctMixed bacterial-fungal skin infection

Mechanism of Action

Dual-action: miconazole disrupts fungal cell membranes via ergosterol inhibition; chlorhexidine provides broad-spectrum antibacterial activity via cell membrane disruption.

Side effects & warnings

Gold standard for concurrent Malassezia and bacterial skin infections. Leave on 10 minutes. Twice weekly initially, then weekly maintenance. Safe for dogs and cats.

Species with Miconazole-Chlorhexidine Shampoo dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugs All Dog (Domestic) drugs

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

· Mason KV, Atwell R: Clinical Efficacy trials on a chlorhexidine/miconazole shampoo for the treatment of seborrheic dermatitis associated with an overgrowth of Malassezia pachydermatis and coccoid bacteria. Proc Eur Soc Vet Dermatol 1995. — Verified against Muller & Kirk's Small Animal Dermatology, 7th Ed, p.238 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.238' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.226; verified by finding the drug named there. If you are holding the book, turn to p.226. — SOURCE EDITION: Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280
· Moriello KA (2004) Treatment of dermatophytosis in dogs and cats: review of published studies. Veterinary Dermatology 15, 99-107; Mueller RS, Bergvall K, Bensignor E et al. (2012) A review of topical therapy for skin infections with bacteria and yeast. Veterinary Dermatology 23, 330-341 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.281 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.281' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.265; verified by finding the drug named there. If you are holding the book, turn to p.265. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705,

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	Topical	See the cited source for the printed regimen	Bathe 2x weekly; 10-min contact time	Strong	Mason KV, Atwell R: Clinical Efficacy trials on a chlorhexidine/miconazole shampoo for the treatment of seborrheic dermatitis associated with an overgrowth of Malassezia pachydermatis and coccoid bacteria. Proc Eur Soc Vet Dermatol 1995. — Verified against Muller & Kirk's Small Animal Dermatology, 7th Ed, p.238 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.238' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.226; verified by finding the drug named there. If you are holding the book, turn to p.226. — SOURCE EDITION: Muller & Kirk's Small Animal Dermatology — ISBN 9781416000280, https://openlibrary.org/isbn/9781416000280
Cat (Domestic)	Topical	See the cited source for the printed regimen	Bathe 2x weekly; 10-min contact time	Moderate

Upgrade for Full Details

Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.

View Plans