Reptile · Python regius · typical adult weight 1.00–2.00 kg
Midazolam is dosed at 1–2 mg/kg IM once in ball pythons, per Larouche CB, Beaufrère H, Mosley C, et al. Evaluation of the effects of midazolam and flumazenil in the ball python (Python regius). J Zoo Wildl Med. 2019;50:579-588. doi:10.1638/2019-0024; Miller LJ, Fetterer DP, Garza NL, et al. A fixed moderate-dose combination of tiletamine+zolazepam outperforms midazolam in induction of short-term immobilization of ball pythons (Python regius). PLoS ONE. 2018;13:1-15. doi:10.1371/journal.pone.0199339 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.246 (2026-08-01).. Midazolam is used in ball pythons for Sedation. Routes documented in ball pythons: IM. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Midazolam in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Versed
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 1–2 mg/kg | once | Single dose | Sedation |
| Larouche CB, Beaufrère H, Mosley C, et al. Evaluation of the effects of midazolam and flumazenil in the ball python (Python regius). J Zoo Wildl Med. 2019;50:579-588. doi:10.1638/2019-0024; Miller LJ, Fetterer DP, Garza NL, et al. A fixed moderate-dose combination of tiletamine+zolazepam outperforms midazolam in induction of short-term immobilization of ball pythons (Python regius). PLoS ONE. 2018;13:1-15. doi:10.1371/journal.pone.0199339 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.246 (2026-08-01). |
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These ranges are per kg. Enter your ball python's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, increasing chloride conductance. Provides anxiolysis, sedation, muscle relaxation, and anticonvulsant effects.
May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Midazolam dose range in ball pythons, with cited source references: IM 1–2 mg/kg once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Midazolam in ball pythons: IM.
Cited course lengths for Midazolam in ball pythons include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Midazolam is indicated in ball pythons for: Sedation.
These are general warnings for Midazolam across species; consult the ball python dosing table above for species-specific guidance. May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Why a species-specific page? Midazolam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.