Cat · Felis catus · typical adult weight 2.50–7.00 kg
Naloxone is dosed at 0.01–0.04 mg/kg IV IV bolus, repeat as needed in cats, per NARCAN INJECTION - Naloxone Hydrochloride Liquid (Solution) for Dogs [US Product Label]. Endo Pharmaceutical Co.; 2017. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.952 (2026-08-01).. Naloxone is used in cats for Opioid reversal. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Naloxone in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Narcan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.01–0.04 mg/kg | IV bolus, repeat as needed | Short duration | Opioid reversal | Strong | NARCAN INJECTION - Naloxone Hydrochloride Liquid (Solution) for Dogs [US Product Label]. Endo Pharmaceutical Co.; 2017. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.952 (2026-08-01). |
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Competitive mu, kappa, and delta opioid receptor antagonist. Rapidly reverses opioid-induced respiratory depression, sedation, and hypotension.
Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Naloxone dose range in cats, with cited source references: IV 0.01–0.04 mg/kg IV bolus, repeat as needed. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Naloxone in cats: IV.
Cited course lengths for Naloxone in cats include: Short duration. Duration depends on the indication — match it to the specific dose rule in the table above.
Naloxone is indicated in cats for: Opioid reversal.
These are general warnings for Naloxone across species; consult the cat dosing table above for species-specific guidance. Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Why a species-specific page? Naloxone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.