Reptile · Pantherophis guttatus · typical adult weight 0.20–0.90 kg
Naloxone is dosed at 0.04–2 mg/kg SC as needed for reversal (no interval given) in corn snakes, per Sladky KK, Kinney ME, Johnson SM. Analgesic efficacy of butorphanol and morphine in bearded dragons and corn snakes. J Am Vet Med Assoc. 2008;233:267-273. (also cited: Sladky KK, Mans C. Clinical analgesia in reptiles. J Exot Pet Med. 2012;21:17-32; Sladky KK, Miletic V, Paul-Murphy J, et al. Analgesic efficacy and respiratory effects of butorphanol and morphine in turtles. J Am Vet Med Assoc. 2007;230:1356-1362.) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.256 doi:10.2460/javma.233.2.267 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.6 (Analgesic (Including Antiinflammatory) Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Naloxone is used in corn snakes for Mu-opioid agonist reversal. Routes documented in corn snakes: SC. A typical adult corn snake weighs 0.20–0.90 kg. ExoticRx lists 1 cited dose rule for Naloxone in corn snakes, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Narcan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC |
| 0.04–2 mg/kg |
| as needed for reversal (no interval given) |
| Mu-opioid agonist reversal |
| Moderate |
| Sladky KK, Kinney ME, Johnson SM. Analgesic efficacy of butorphanol and morphine in bearded dragons and corn snakes. J Am Vet Med Assoc. 2008;233:267-273. (also cited: Sladky KK, Mans C. Clinical analgesia in reptiles. J Exot Pet Med. 2012;21:17-32; Sladky KK, Miletic V, Paul-Murphy J, et al. Analgesic efficacy and respiratory effects of butorphanol and morphine in turtles. J Am Vet Med Assoc. 2007;230:1356-1362.) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.256 doi:10.2460/javma.233.2.267 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.6 (Analgesic (Including Antiinflammatory) Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.04–2 | SC | Carpenter's Exotic Animal Formulary, 6th edTable 4.6 | 0.04-2 mg/kg SC,432,434 |
| 4 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 4.5 | 4 mg/kg IM |
| 0.04–2 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 | 0.04-2 mg/kg SC304,305,307,309 Corn snakes, bearded dragons, red-eared sliders/μ-opioid agonist reversal |
| 4 | — |
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These ranges are per kg. Enter your corn snake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive mu, kappa, and delta opioid receptor antagonist. Rapidly reverses opioid-induced respiratory depression, sedation, and hypotension.
Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Species-specific contraindications and adverse-reaction reports for corn snakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Naloxone dose range in corn snakes, with cited source references: SC 0.04–2 mg/kg as needed for reversal (no interval given). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Naloxone in corn snakes: SC.
Naloxone is indicated in corn snakes for: Mu-opioid agonist reversal.
These are general warnings for Naloxone across species; consult the corn snake dosing table above for species-specific guidance. Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Why a species-specific page? Naloxone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in corn snakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.5 |
| 4 mg/kg IM95 Green tree monitors/reversal of butorphanol |
| 0.04–2 | SC | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.6 | 0.04-2 mg/kg SC (Sladky KK, unpublished data)304,307,309 Red-eared sliders, bearded dragons, corn snakes/μ-opioid agonist reversal |
| 10 | SC | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 10 mg/kg SC;27 titrate to effect Antagonist for buprenorphine, butorphanol, codeine, fentanyl, morphine |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.