Reptile · Pantherophis guttatus · typical adult weight 0.20–0.90 kg
Naloxone is dosed at 0.04–2 mg/kg SC as needed for reversal (no interval given) in corn snakes, per Sladky KK, Kinney ME, Johnson SM. Analgesic efficacy of butorphanol and morphine in bearded dragons and corn snakes. J Am Vet Med Assoc. 2008;233:267-273. (also cited: Sladky KK, Mans C. Clinical analgesia in reptiles. J Exot Pet Med. 2012;21:17-32; Sladky KK, Miletic V, Paul-Murphy J, et al. Analgesic efficacy and respiratory effects of butorphanol and morphine in turtles. J Am Vet Med Assoc. 2007;230:1356-1362.) — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.256 (2026-08-01, PENDING REVIEW) doi:10.2460/javma.233.2.267. Naloxone is used in corn snakes for Mu-opioid agonist reversal. Routes documented in corn snakes: SC. A typical adult corn snake weighs 0.20–0.90 kg. ExoticRx lists 1 cited dose rule for Naloxone in corn snakes, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Narcan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 0.04–2 mg/kg | as needed for reversal (no interval given) | Mu-opioid agonist reversal | Moderate | Sladky KK, Kinney ME, Johnson SM. Analgesic efficacy of butorphanol and morphine in bearded dragons and corn snakes. J Am Vet Med Assoc. 2008;233:267-273. (also cited: Sladky KK, Mans C. Clinical analgesia in reptiles. J Exot Pet Med. 2012;21:17-32; Sladky KK, Miletic V, Paul-Murphy J, et al. Analgesic efficacy and respiratory effects of butorphanol and morphine in turtles. J Am Vet Med Assoc. 2007;230:1356-1362.) — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.256 (2026-08-01, PENDING REVIEW) doi:10.2460/javma.233.2.267 |
Need the exact dose for your patient?
These ranges are per kg. Enter your corn snake's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive mu, kappa, and delta opioid receptor antagonist. Rapidly reverses opioid-induced respiratory depression, sedation, and hypotension.
Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Species-specific contraindications and adverse-reaction reports for corn snakes may differ from canine / feline reference data — consult the primary citations listed with each rule.
Naloxone dose range in corn snakes, with cited source references: SC 0.04–2 mg/kg as needed for reversal (no interval given). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Naloxone in corn snakes: SC.
Naloxone is indicated in corn snakes for: Mu-opioid agonist reversal.
These are general warnings for Naloxone across species; consult the corn snake dosing table above for species-specific guidance. Very short duration (30-60 min) — renarcotization risk with long-acting opioids. May precipitate acute withdrawal, pain, and sympathetic surge. Repeat dosing often needed.
Why a species-specific page? Naloxone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in corn snakes — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.