Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Pentosan Polysulfate is dosed at 3 mg/kg SC q5-7d in guinea pigs, per Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW). Pentosan Polysulfate is used in guinea pigs for Osteoarthritis; idiopathic cystitis. Routes documented in guinea pigs: SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Pentosan Polysulfate in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cartrophen Vet, Elmiron
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 3 mg/kg | q5-7d | Osteoarthritis; idiopathic cystitis | Moderate | Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Semi-synthetic polysulfated xylanopyranose. Stimulates proteoglycan synthesis, inhibits catabolic enzymes, improves blood flow to subchondral bone.
SC injection series for OA (weekly x 4). May affect coagulation. Also used for feline interstitial cystitis (oral). Not available in USA (available in Australia, EU).
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pentosan Polysulfate dose range in guinea pigs, with cited source references: SC 3 mg/kg q5-7d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pentosan Polysulfate in guinea pigs: SC.
Pentosan Polysulfate is indicated in guinea pigs for: Osteoarthritis; idiopathic cystitis.
These are general warnings for Pentosan Polysulfate across species; consult the guinea pig dosing table above for species-specific guidance. SC injection series for OA (weekly x 4). May affect coagulation. Also used for feline interstitial cystitis (oral). Not available in USA (available in Australia, EU).
Why a species-specific page? Pentosan Polysulfate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.