ExoticRx · exoticrx.com/drugs/perampanel
US brand names:Fycompa
Perampanel is dosed at 0.5–2 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
First-in-class selective non-competitive AMPA-type glutamate receptor antagonist. Reduces excitatory glutamatergic neurotransmission.
Aggression and hostility reported. Dose-related dizziness and somnolence. Schedule III controlled substance. No veterinary pharmacokinetic data published.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.