Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Pergolide (Equine) is dosed at 0.002 mg/kg PO q24h in horses, per PRASCEND - Pergolide Tablet [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=455e5d97-f639-472b-b93b-88b9174a0310 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1032 (2026-08-01).. Pergolide (Equine) is used in horses for Pituitary pars intermedia dysfunction (PPID/Cushing's). Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Pergolide (Equine) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Prascend
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.002 mg/kg | q24h | Lifelong | Pituitary pars intermedia dysfunction (PPID/Cushing's) | Strong | PRASCEND - Pergolide Tablet [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=455e5d97-f639-472b-b93b-88b9174a0310 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1032 (2026-08-01). |
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Dopamine D2 receptor agonist that inhibits melanotroph proliferation and ACTH secretion from the pars intermedia of the pituitary gland.
Treatment for pituitary pars intermedia dysfunction (PPID / equine Cushing's disease). Start at low dose and titrate. May cause transient inappetence. Monitor ACTH levels to titrate dose. Long-term/lifelong treatment.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pergolide (Equine) dose range in horses, with cited source references: PO 0.002 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pergolide (Equine) in horses: PO.
Cited course lengths for Pergolide (Equine) in horses include: Lifelong. Duration depends on the indication — match it to the specific dose rule in the table above.
Pergolide (Equine) is indicated in horses for: Pituitary pars intermedia dysfunction (PPID/Cushing's).
These are general warnings for Pergolide (Equine) across species; consult the horse dosing table above for species-specific guidance. Treatment for pituitary pars intermedia dysfunction (PPID / equine Cushing's disease). Start at low dose and titrate. May cause transient inappetence. Monitor ACTH levels to titrate dose. Long-term/lifelong treatment.
Why a species-specific page? Pergolide (Equine) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.