Pergolide (Equine) for Horse
Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Pergolide (Equine) is used in horse for Pituitary pars intermedia dysfunction (PPID/Cushing's). Routes documented in horse: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Pergolide (Equine) in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Prascend
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.002 mg/kg | q24h | Lifelong | Pituitary pars intermedia dysfunction (PPID/Cushing's) | Strong | FDA NADA Label |
Need the exact dose for your patient?
These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Dopamine D2 receptor agonist that inhibits melanotroph proliferation and ACTH secretion from the pars intermedia of the pituitary gland.
Side effects & warnings
Treatment for pituitary pars intermedia dysfunction (PPID / equine Cushing's disease). Start at low dose and titrate. May cause transient inappetence. Monitor ACTH levels to titrate dose. Long-term/lifelong treatment.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Endocrine drugs with horse dosing
Why a species-specific page? Pergolide (Equine) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.