Skip to main content

Cloprostenol Sodium (Livestock) for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Cloprostenol Sodium (Livestock) is used in horse for Luteolysis, Estrus synchronization. Routes documented in horse: IM. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Cloprostenol Sodium (Livestock) in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Estrumate, estroPLAN

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.25 mg totalsingle doseLuteolysisModeratePlumb's Veterinary Drug Handbook, 9th Ed
IM250 mcg total doseOnceSingle injectionEstrus synchronizationStrongFDA NADA Label

Need the exact dose for your patient?

These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

Calculate for this horse

Mechanism of action

Synthetic analogue of prostaglandin F2-alpha. More potent and longer-acting than natural dinoprost. Causes luteolysis and return to estrus in cattle and horses.

Side effects & warnings

Women of childbearing age should handle with extreme caution. Absorbed through skin. Fewer side effects than dinoprost in horses. IM injection only.

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with horse dosing

Cloprostenol Sodium (Livestock) dosing in other species

Why a species-specific page? Cloprostenol Sodium (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.