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Cloprostenol Sodium (Livestock) for Cattle

Livestock · Bos taurus · typical adult weight 250.00–900.00 kg

Cloprostenol Sodium (Livestock) is used in cattle for Estrus synchronization, luteolysis, Estrus synchronization, pyometra. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Cloprostenol Sodium (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Estrumate, estroPLAN

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.5 mg totalsingle doseEstrus synchronization, luteolysisStrongFDA NADA Label
IM500 mcg total dosePer protocol1-2 injectionsEstrus synchronization, pyometraStrongFDA NADA Label

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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Synthetic analogue of prostaglandin F2-alpha. More potent and longer-acting than natural dinoprost. Causes luteolysis and return to estrus in cattle and horses.

Side effects & warnings

Women of childbearing age should handle with extreme caution. Absorbed through skin. Fewer side effects than dinoprost in horses. IM injection only.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with cattle dosing

Cloprostenol Sodium (Livestock) dosing in other species

Why a species-specific page? Cloprostenol Sodium (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.