Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Melengestrol Acetate is dosed at 0.5 mg/head/day in feed PO q24h in feed in cattle, per Verified against Riviere & Papich, Veterinary Pharmacology and Therapeutics, 10th Ed, p.707 (2026-08-01). — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829. Melengestrol Acetate is used in cattle for Estrus suppression in feedlot heifers, Estrus suppression, synchronization. Routes documented in cattle: PO. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Melengestrol Acetate in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: MGA
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5 mg/head/day in feedmax 0.5 mg total | q24h in feed | 14 days for sync; continuous for suppression | Estrus suppression in feedlot heifers | Strong | Verified against Riviere & Papich, Veterinary Pharmacology and Therapeutics, 10th Ed, p.707 (2026-08-01). — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829 |
| PO | 0.5 mg/head/day | q24h in feed | 14 days | Estrus suppression, synchronization | Strong | Verified against Riviere & Papich, Veterinary Pharmacology and Therapeutics, 10th Ed, p.707 (2026-08-01). — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829 |
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Synthetic progestogen that suppresses estrus and ovulation in heifers by negative feedback on gonadotropin secretion. Also has mild growth-promoting effects.
For heifers only. Do not use in dairy cows or breeding animals. Used in estrus synchronization protocols (MGA + prostaglandin). No withdrawal period for meat at approved doses. Not for use in animals intended for breeding during treatment.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Melengestrol Acetate dose ranges in cattle, with cited source references: PO 0.5 mg/head/day in feed q24h in feed; PO 0.5 mg/head/day q24h in feed. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Melengestrol Acetate in cattle: PO.
Cited course lengths for Melengestrol Acetate in cattle include: 14 days for sync; continuous for suppression; 14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Melengestrol Acetate is indicated in cattle for: Estrus suppression in feedlot heifers, Estrus suppression, synchronization.
These are general warnings for Melengestrol Acetate across species; consult the cattle dosing table above for species-specific guidance. For heifers only. Do not use in dairy cows or breeding animals. Used in estrus synchronization protocols (MGA + prostaglandin). No withdrawal period for meat at approved doses. Not for use in animals intended for breeding during treatment.
Why a species-specific page? Melengestrol Acetate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.