Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Gonadorelin (GnRH) is dosed at 0.1 mg total IM single dose in cattle, per FACTREL - Gonadorelin Hydrochloride Injection [US Product Label for Cattle]. Zoetis Inc.; 2015. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1451663c-b85a-4b45-8b27-6d572d0032f9 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.619 (2026-08-01). — Plumb's 10th ed (held) printed p.591, Gonadorelin monograph spanning p.591-592; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Gonadorelin (GnRH) is used in cattle for Ovulation induction, cystic ovarian disease, Ovsynch/timed AI, ovarian cysts. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Gonadorelin (GnRH) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Factrel, Fertagyl, Cystorelin, OvaCyst
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.1 mg total | single dose | — | Ovulation induction, cystic ovarian disease | Strong | FACTREL - Gonadorelin Hydrochloride Injection [US Product Label for Cattle]. Zoetis Inc.; 2015. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1451663c-b85a-4b45-8b27-6d572d0032f9 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.619 (2026-08-01). — Plumb's 10th ed (held) printed p.591, Gonadorelin monograph spanning p.591-592; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| IM | 100 mcg total dose | Per synchronization protocol | Per Ovsynch/CoSynch protocol | Ovsynch/timed AI, ovarian cysts | Strong | FACTREL - Gonadorelin Hydrochloride Injection [US Product Label for Cattle]. Zoetis Inc.; 2015. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1451663c-b85a-4b45-8b27-6d572d0032f9 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.619 (2026-08-01). — Plumb's 10th ed (held) printed p.591, Gonadorelin monograph spanning p.591-592; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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Synthetic gonadotropin-releasing hormone (GnRH) that stimulates release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. Causes ovulation or luteinization of follicles.
Used in timed AI protocols (Ovsynch, CoSynch) in cattle. No withdrawal period required. Response depends on stage of estrous cycle and presence of a dominant follicle.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Gonadorelin (GnRH) dose ranges in cattle, with cited source references: IM 0.1 mg total single dose; IM 100 mcg total dose Per synchronization protocol. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Gonadorelin (GnRH) in cattle: IM.
Cited course lengths for Gonadorelin (GnRH) in cattle include: Per Ovsynch/CoSynch protocol. Duration depends on the indication — match it to the specific dose rule in the table above.
Gonadorelin (GnRH) is indicated in cattle for: Ovulation induction, cystic ovarian disease, Ovsynch/timed AI, ovarian cysts.
These are general warnings for Gonadorelin (GnRH) across species; consult the cattle dosing table above for species-specific guidance. Used in timed AI protocols (Ovsynch, CoSynch) in cattle. No withdrawal period required. Response depends on stage of estrous cycle and presence of a dominant follicle.
Why a species-specific page? Gonadorelin (GnRH) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.