Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Dinoprost Tromethamine (Livestock) is dosed at 25 mg total IM single dose in cattle, per Lutalyse sterile - dinoprost trimethamine injection, solution [US product label]. Kalamazoo, MI: Zoetis; 2016. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=38c5cefd-b3d2-41d4-a2fb-0d6c45d02529 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.435 (2026-08-01).. Dinoprost Tromethamine (Livestock) is used in cattle for Luteolysis, synchronization, abortion, Estrus synchronization, pyometra. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Dinoprost Tromethamine (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lutalyse, ProstaMate
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 25 mg total | single dose | — | Luteolysis, synchronization, abortion | Strong | Lutalyse sterile - dinoprost trimethamine injection, solution [US product label]. Kalamazoo, MI: Zoetis; 2016. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=38c5cefd-b3d2-41d4-a2fb-0d6c45d02529 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.435 (2026-08-01). |
| IM | 25 mg total dosemax 25 mg total | Per synchronization protocol | 1-2 injections per protocol | Estrus synchronization, pyometra | Strong | Lutalyse sterile - dinoprost trimethamine injection, solution [US product label]. Kalamazoo, MI: Zoetis; 2016. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=38c5cefd-b3d2-41d4-a2fb-0d6c45d02529 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.435 (2026-08-01). |
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Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.
Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dinoprost Tromethamine (Livestock) dose ranges in cattle, with cited source references: IM 25 mg total single dose; IM 25 mg total dose Per synchronization protocol. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dinoprost Tromethamine (Livestock) in cattle: IM.
Cited course lengths for Dinoprost Tromethamine (Livestock) in cattle include: 1-2 injections per protocol. Duration depends on the indication — match it to the specific dose rule in the table above.
Dinoprost Tromethamine (Livestock) is indicated in cattle for: Luteolysis, synchronization, abortion, Estrus synchronization, pyometra.
These are general warnings for Dinoprost Tromethamine (Livestock) across species; consult the cattle dosing table above for species-specific guidance. Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.
Why a species-specific page? Dinoprost Tromethamine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.