Dinoprost Tromethamine (Livestock) for Cattle
Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Dinoprost Tromethamine (Livestock) is used in cattle for Luteolysis, synchronization, abortion, Estrus synchronization, pyometra. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 2 cited dose rules for Dinoprost Tromethamine (Livestock) in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Lutalyse, ProstaMate
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 25 mg total | single dose | — | Luteolysis, synchronization, abortion | Strong | FDA NADA Label |
| IM | 25 mg total dose | Per synchronization protocol | 1-2 injections per protocol | Estrus synchronization, pyometra | Strong | FDA NADA Label |
Absolute dose ceiling, regardless of body weight: 25 mg total (IM).
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.
Side effects & warnings
Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Endocrine drugs with cattle dosing
Dinoprost Tromethamine (Livestock) dosing in other species
Why a species-specific page? Dinoprost Tromethamine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.