Dinoprost Tromethamine (Livestock) for Horse
Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Dinoprost Tromethamine (Livestock) is used in horse for Luteolysis, endometritis treatment, Estrus synchronization. Routes documented in horse: IM. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Dinoprost Tromethamine (Livestock) in horse, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Lutalyse, ProstaMate
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 5–10 mg total | single dose | — | Luteolysis, endometritis treatment | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IM | 5–10 mg total dose | Once | Single injection | Estrus synchronization | Strong | FDA NADA Label |
Absolute dose ceiling, regardless of body weight: 10 mg total (IM).
Need the exact dose for your patient?
These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Natural prostaglandin F2-alpha that causes luteolysis (regression of the corpus luteum), resulting in a decline in progesterone and return to estrus. Also causes uterine contraction and cervical relaxation.
Side effects & warnings
Do not handle if pregnant or have asthma — absorbed through skin and may cause bronchospasm or abortion. Wear protective gloves. Transient side effects include sweating, increased respiration, and mild colic in mares.
Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Endocrine drugs with horse dosing
Dinoprost Tromethamine (Livestock) dosing in other species
Why a species-specific page? Dinoprost Tromethamine (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.