Cat · Felis catus · typical adult weight 2.50–7.00 kg
Piroxicam is dosed at 0.3 mg/kg PO q48h in cats, per Marconato L, Buchholz J, Keller M, Bettini G, Valenti P, Kaser-Hotz B. Multimodal therapeutic approach and interdisciplinary challenge for the treatment of unresectable head and neck squamous cell carcinoma in six cats: a pilot study. Vet Comp Oncol. 2013;11(2):101-112. doi:10.1111/j.1476-5829.2011.00304.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1062 (2026-08-01). — Plumb's 10th ed (held) printed p.1033, Piroxicam monograph spanning p.1033-1034; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Piroxicam is used in cats for Squamous cell carcinoma (adjunctive). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Piroxicam in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Feldene
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.3 mg/kg | q48h | Long-term | Squamous cell carcinoma (adjunctive) | Weak | Marconato L, Buchholz J, Keller M, Bettini G, Valenti P, Kaser-Hotz B. Multimodal therapeutic approach and interdisciplinary challenge for the treatment of unresectable head and neck squamous cell carcinoma in six cats: a pilot study. Vet Comp Oncol. 2013;11(2):101-112. doi:10.1111/j.1476-5829.2011.00304.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1062 (2026-08-01). — Plumb's 10th ed (held) printed p.1033, Piroxicam monograph spanning p.1033-1034; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.3 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.346 | 0.3 mg/kg p.o. q24-96h; start at least frequent administration and slowly increase if no side effec |
| 0.3 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.673 | • 0.3 mg/kg q24h PO. A common dose is 1 mg per cat q24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Non-selective COX inhibitor. Also has anti-tumor properties via COX-independent mechanisms (apoptosis, anti-angiogenic).
Used primarily as adjunctive cancer therapy (transitional cell carcinoma). GI ulceration common. Renal toxicity. Give with food. Concurrent use of misoprostol recommended.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Piroxicam dose range in cats, with cited source references: PO 0.3 mg/kg q48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Piroxicam in cats: PO.
Cited course lengths for Piroxicam in cats include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Piroxicam is indicated in cats for: Squamous cell carcinoma (adjunctive).
These are general warnings for Piroxicam across species; consult the cat dosing table above for species-specific guidance. Used primarily as adjunctive cancer therapy (transitional cell carcinoma). GI ulceration common. Renal toxicity. Give with food. Concurrent use of misoprostol recommended.
Why a species-specific page? Piroxicam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.