Cat · Felis catus · typical adult weight 2.50–7.00 kg
Prednisolone Oral is dosed at 1–4 mg/kg PO q12-24h, taper over weeks in cats, per Reusch CE. Glucocorticoid therapy. In: Feldman E, Nelson R, Reusch C, Scott-Moncrieff J, Behrend E, eds. Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:555-577. / 24. Blois SL, Mathews K. Anti-inflammatory therapy. In: Ettinger S, Feldman B, Cote E, eds. Textbook of Veterinary Internal Medicine. 8th ed. Elsevier; 2017:695-700. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1088 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.1088' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1061; verified by finding the drug named there. If you are holding the book, turn to p.1061. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Prednisolone Oral is used in cats for Inflammatory/immune-mediated disease. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Prednisolone Oral in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Prednis-Tab
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–4 mg/kg | q12-24h, taper over weeks | Variable | Inflammatory/immune-mediated disease | Strong | Reusch CE. Glucocorticoid therapy. In: Feldman E, Nelson R, Reusch C, Scott-Moncrieff J, Behrend E, eds. Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:555-577. / 24. Blois SL, Mathews K. Anti-inflammatory therapy. In: Ettinger S, Feldman B, Cote E, eds. Textbook of Veterinary Internal Medicine. 8th ed. Elsevier; 2017:695-700. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1088 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.1088' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1061; verified by finding the drug named there. If you are holding the book, turn to p.1061. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5–1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.356 | 0.5-1 mg/kg p.o. q12-24h; taper to 0.5 mg/ kg q48h. |
| 1–2 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.356 | 1-2 mg/kg p.o. q12-24h, tapering slowly to 0.5-1 mg/kg q48h (for many conditions this will tak |
| 0.5–1 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.356 | 1-2 mg/kg p.o. q12-24h, tapering slowly to 0.5-1 mg/kg q48h (for many conditions this will take 6 months). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Active glucocorticoid (does not require hepatic conversion unlike prednisone). Preferred in cats (poor prednisone-to-prednisolone conversion).
Preferred over prednisone in cats and patients with hepatic disease. Same side effects as other glucocorticoids: PU/PD, polyphagia, iatrogenic Cushing's.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Prednisolone Oral dose range in cats, with cited source references: PO 1–4 mg/kg q12-24h, taper over weeks. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Prednisolone Oral in cats: PO.
Cited course lengths for Prednisolone Oral in cats include: Variable. Duration depends on the indication — match it to the specific dose rule in the table above.
Prednisolone Oral is indicated in cats for: Inflammatory/immune-mediated disease.
These are general warnings for Prednisolone Oral across species; consult the cat dosing table above for species-specific guidance. Preferred over prednisone in cats and patients with hepatic disease. Same side effects as other glucocorticoids: PU/PD, polyphagia, iatrogenic Cushing's.
Why a species-specific page? Prednisolone Oral pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 15–30 |
| IV |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.695 |
| • Shock (effectiveness of this use is controversial): 15-30 mg/kg IV (repeat in |
| 1–2 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.695 | • CNS trauma: 15-30 mg/kg IV, taper to 1-2 mg/kg q12h. |
| 1 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.695 | • Anti-inflammatory: 1 mg/kg/day IV. |
| 0.25–0.5 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.695 | • Replacement therapy: 0.25-0.5 mg/kg/day IV. |
| 10 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.695 | • Intermittent treatment (pulse therapy) of pemphigus foliaceus: 10 mg/kg IV. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.