Cat · Felis catus · typical adult weight 2.50–7.00 kg
Pregabalin is dosed at 1–2 mg/kg PO q12h in cats, per BSAVA Small Animal Formulary, 10th ed, Part A — Canine and Feline, Pregabalin, DOSES, printed p.341 (corpus PDF p.357): "Cats: 1-2 mg/kg p.o. q12h (limited anecdotal evidence)", under a Use section listing both "Adjunctive therapy in the treatment of epileptic seizures refractory to conventional treatment" and "Treatment of neuropathic pain". Corroborated: Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.674 (corpus PDF p.702): "Cats • Anticonvulsant dose or neuropathic pain dose: start with 2 mg/kg q12h PO and increase to 4 mg/kg q12h PO." Plumb's Veterinary Drug Handbook, 10th ed (held), printed p.1065 (corpus PDF p.1092), CATS, prints the served figure under a seizure heading: "Seizure disorders (extra-label): Anecdotally, 1 - 2 mg/kg PO every 12 hours is most commonly mentioned." [INDICATION CORRECTED 2026-08-12, two readers — "anxiety" is removed because the printed feline anxiolytic figure is 5-10 mg/kg, five times the served dose.] — SOURCE EDITIONS: BSAVA Small Animal Formulary, Part A — ISBN 9781910443705; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855; Plumb's Veterinary Drug Handbook — ISBN 9781394172207. Pregabalin is used in cats for Seizure disorders (adjunctive) or neuropathic pain. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Pregabalin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lyrica
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q12h | Long-term; taper to discontinue | Seizure disorders (adjunctive) or neuropathic pain | Weak | BSAVA Small Animal Formulary, 10th ed, Part A — Canine and Feline, Pregabalin, DOSES, printed p.341 (corpus PDF p.357): "Cats: 1-2 mg/kg p.o. q12h (limited anecdotal evidence)", under a Use section listing both "Adjunctive therapy in the treatment of epileptic seizures refractory to conventional treatment" and "Treatment of neuropathic pain". Corroborated: Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, printed p.674 (corpus PDF p.702): "Cats • Anticonvulsant dose or neuropathic pain dose: start with 2 mg/kg q12h PO and increase to 4 mg/kg q12h PO." Plumb's Veterinary Drug Handbook, 10th ed (held), printed p.1065 (corpus PDF p.1092), CATS, prints the served figure under a seizure heading: "Seizure disorders (extra-label): Anecdotally, 1 - 2 mg/kg PO every 12 hours is most commonly mentioned." [INDICATION CORRECTED 2026-08-12, two readers — "anxiety" is removed because the printed feline anxiolytic figure is 5-10 mg/kg, five times the served dose.] — SOURCE EDITIONS: BSAVA Small Animal Formulary, Part A — ISBN 9781910443705; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855; Plumb's Veterinary Drug Handbook — ISBN 9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 1–2 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.357 | 1-2 mg/kg p.o. q12h (limited anecdotal evidence). |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds alpha-2-delta subunit of voltage-gated calcium channels with higher affinity than gabapentin. Reduces excitatory neurotransmitter release. More predictable pharmacokinetics than gabapentin.
Controlled substance (CV). Sedation and ataxia at higher doses. More potent than gabapentin — lower doses needed. Taper to discontinue. Monitor for weight gain.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pregabalin dose range in cats, with cited source references: PO 1–2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pregabalin in cats: PO.
Cited course lengths for Pregabalin in cats include: Long-term; taper to discontinue. Duration depends on the indication — match it to the specific dose rule in the table above.
Pregabalin is indicated in cats for: Seizure disorders (adjunctive) or neuropathic pain.
These are general warnings for Pregabalin across species; consult the cat dosing table above for species-specific guidance. Controlled substance (CV). Sedation and ataxia at higher doses. More potent than gabapentin — lower doses needed. Taper to discontinue. Monitor for weight gain.
Why a species-specific page? Pregabalin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.