Cat · Felis catus · typical adult weight 2.50–7.00 kg
Pregabalin is dosed at 1–2 mg/kg PO q12h in cats, per Munana K. Current Approaches to Seizure Management. Presented at: ACVIM Forum; 2010. Distributed by John Wiley & Sons, Inc. PMID: 42314398 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1092 (2026-08-01).. Pregabalin is used in cats for Neuropathic pain, anxiety. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Pregabalin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lyrica
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q12h | Long-term; taper to discontinue | Neuropathic pain, anxiety | Weak | Munana K. Current Approaches to Seizure Management. Presented at: ACVIM Forum; 2010. Distributed by John Wiley & Sons, Inc. PMID: 42314398 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1092 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds alpha-2-delta subunit of voltage-gated calcium channels with higher affinity than gabapentin. Reduces excitatory neurotransmitter release. More predictable pharmacokinetics than gabapentin.
Controlled substance (CV). Sedation and ataxia at higher doses. More potent than gabapentin — lower doses needed. Taper to discontinue. Monitor for weight gain.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pregabalin dose range in cats, with cited source references: PO 1–2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pregabalin in cats: PO.
Cited course lengths for Pregabalin in cats include: Long-term; taper to discontinue. Duration depends on the indication — match it to the specific dose rule in the table above.
Pregabalin is indicated in cats for: Neuropathic pain, anxiety.
These are general warnings for Pregabalin across species; consult the cat dosing table above for species-specific guidance. Controlled substance (CV). Sedation and ataxia at higher doses. More potent than gabapentin — lower doses needed. Taper to discontinue. Monitor for weight gain.
Why a species-specific page? Pregabalin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.