Cat · Felis catus · typical adult weight 2.50–7.00 kg
Pretomanid is used in cat for MDR mycobacterial infections. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Pretomanid in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: PA-824
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 3–6 mg/kg | q24h | 26 weeks (combination therapy) | MDR mycobacterial infections | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Prodrug activated by mycobacterial nitroreductase. Inhibits mycolic acid synthesis and generates reactive nitrogen species under anaerobic conditions.
Hepatotoxicity. Used in combination with bedaquiline and linezolid (BPaL regimen). No veterinary data.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Pretomanid pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.