ExoticRx · exoticrx.com/drugs/propylthiouracil
US brand names:PTU
Propylthiouracil is dosed at 50 mg per cat PO q12h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Inhibits thyroid peroxidase-mediated iodination and coupling reactions, and at high doses inhibits peripheral T4 to T3 conversion.
Higher hepatotoxicity and immune-mediated reactions than methimazole. Not recommended in cats — methimazole preferred. Monitor CBC and liver function.
Species references:All Cat (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 50 mg per cat | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.