ExoticRx · exoticrx.com/drugs/quetiapine
US brand names:Seroquel
Antagonist at serotonin 5-HT2A, dopamine D1 and D2, histamine H1, and adrenergic alpha-1 receptors. Metabolite norquetiapine inhibits norepinephrine transporter.
Sedation is common and dose-related. May cause metabolic changes (weight gain, hyperglycemia). Risk of extrapyramidal signs. Very limited veterinary data.
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