Livestock · Sus scrofa domesticus · typical adult weight 1.00–300.00 kg
Sulfamethazine is dosed at 110–220 mg/kg PO Loading dose then continuous in swine, per US FDA. Sulmet (sodium sulfamethazine) Soluble Powder, NADA 122-272, Huvepharma. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=09658aaf-dd0f-462c-8a76-538be39b4689 - cattle, calves, swine, chickens, turkeys; swine 237.6 mg/kg day 1 then 118.8 mg/kg days 2-4, max 5 days; swine withdrawal 15 days. — 21 CFR § 520.2261b (Sulfamethazine powder), conditions of use for Swine: 119.05-119.05 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.670. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-520.2261b. Sulfamethazine is used in swine for Bacterial pneumonia, necrotic enteritis. Routes documented in swine: PO. A typical adult swine weighs 1.00–300.00 kg. ExoticRx lists 1 cited dose rule for Sulfamethazine in swine, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Sulmet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 110–220 mg/kg | Loading dose then continuous | Loading then 4 days | Bacterial pneumonia, necrotic enteritis | Strong | US FDA. Sulmet (sodium sulfamethazine) Soluble Powder, NADA 122-272, Huvepharma. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=09658aaf-dd0f-462c-8a76-538be39b4689 - cattle, calves, swine, chickens, turkeys; swine 237.6 mg/kg day 1 then 118.8 mg/kg days 2-4, max 5 days; swine withdrawal 15 days. — 21 CFR § 520.2261b (Sulfamethazine powder), conditions of use for Swine: 119.05-119.05 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.670. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-520.2261b |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 237 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.781 | • Use of soluble powder as a drench or in drinking water: 237 mg/kg as initial |
| 119 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.781 | dose, followed by 119 mg/kg q24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your swine's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits dihydropteroate synthase in bacterial folate synthesis. Used primarily in food animals and poultry for coccidiosis.
Withdrawal times required in food animals. Crystalluria risk. Adequate water intake essential. May cause blood dyscrasias with prolonged use.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sulfamethazine dose range in swine, with cited source references: PO 110–220 mg/kg Loading dose then continuous. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sulfamethazine in swine: PO.
Cited course lengths for Sulfamethazine in swine include: Loading then 4 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Sulfamethazine is indicated in swine for: Bacterial pneumonia, necrotic enteritis.
These are general warnings for Sulfamethazine across species; consult the swine dosing table above for species-specific guidance. Withdrawal times required in food animals. Crystalluria risk. Adequate water intake essential. May cause blood dyscrasias with prolonged use.
Why a species-specific page? Sulfamethazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.