Cat · Felis catus · typical adult weight 2.50–7.00 kg
Tacrolimus Oral is used in cat for Immune-mediated disease (refractory). Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Tacrolimus Oral in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Prograf
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.05–0.1 mg/kg | q12h | Long-term; monitor drug levels | Immune-mediated disease (refractory) | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds FKBP12, inhibiting calcineurin and blocking IL-2 transcription. More potent immunosuppressant than cyclosporine (10-100x in vitro).
Nephrotoxic and diabetogenic. Monitor drug levels, renal function, and blood glucose. Drug interactions with CYP3A4 substrates. Very narrow therapeutic index.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Tacrolimus Oral pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.