ExoticRx · exoticrx.com/drugs/thiamylal
US brand names:Bio-Tal, Surital
Thiamylal is dosed at 8–18 mg/kg IV Single dose (induction) in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database. Verify against current literature before clinical use.
Ultra-short-acting thiobarbiturate that enhances GABA-A receptor activity, producing rapid-onset general anesthesia. Highly lipophilic with redistribution-dependent recovery.
Perivascular injection causes severe tissue necrosis. Respiratory depression and apnea common. Sighthounds (greyhounds) have prolonged recovery due to low body fat. Largely replaced by propofol.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 8–18 mg/kg | Single dose (induction) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Cat (Domestic) | IV | 8–15 mg/kg | Single dose (induction) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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