ExoticRx · exoticrx.com/drugs/tiagabine
US brand names:Gabitril
Tiagabine is dosed at 0.5–2 mg/kg PO q8h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Selectively inhibits GABA uptake into neurons and glia by blocking GAT-1 transporter, prolonging GABA availability in the synaptic cleft.
May cause sedation, dizziness, and tremor. Potential for non-convulsive status epilepticus. Very limited veterinary data. Use with caution.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–2 mg/kg | q8h | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.