ExoticRx · exoticrx.com/drugs/tiludronate
US brand names:Tildren
Tiludronate is dosed at 0.1–0.3 mg/kg IV IV infusion q28 days in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Bisphosphonate that inhibits osteoclast-mediated bone resorption by binding to hydroxyapatite in bone. Does not impair bone mineralization.
FDA-approved for navicular disease in horses. IV infusion over 90 minutes. Transient colic, renal toxicity at high doses. Do not use in horses with renal disease.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.1–0.3 mg/kg | IV infusion q28 days | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.