Pocket Pet · Rattus norvegicus var. domestica · typical adult weight 0.25–0.70 kg
Trimethoprim-Sulfamethoxazole is dosed at 30 mg/kg PO q12h in pet rats, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1223 (2026-08-01).. Trimethoprim-Sulfamethoxazole is used in pet rats for Strep pneumoniae / secondary cover. Routes documented in pet rats: PO. A typical adult pet rat weighs 0.25–0.70 kg. ExoticRx lists 1 cited dose rule for Trimethoprim-Sulfamethoxazole in pet rats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Bactrim, TMS
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 30 mg/kg | q12h | Strep pneumoniae / secondary cover | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1223 (2026-08-01). |
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These ranges are per kg. Enter your pet rat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Sequential blockade of folate synthesis: sulfamethoxazole inhibits dihydropteroate synthase; trimethoprim inhibits dihydrofolate reductase.
May cause keratoconjunctivitis sicca (KCS) in dogs with prolonged use. Can cause bone marrow suppression. Avoid in animals with hepatic disease. Adequate hydration required.
Species-specific contraindications and adverse-reaction reports for pet rats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Trimethoprim-Sulfamethoxazole dose range in pet rats, with cited source references: PO 30 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Trimethoprim-Sulfamethoxazole in pet rats: PO.
Trimethoprim-Sulfamethoxazole is indicated in pet rats for: Strep pneumoniae / secondary cover.
These are general warnings for Trimethoprim-Sulfamethoxazole across species; consult the pet rat dosing table above for species-specific guidance. May cause keratoconjunctivitis sicca (KCS) in dogs with prolonged use. Can cause bone marrow suppression. Avoid in animals with hepatic disease. Adequate hydration required.
Why a species-specific page? Trimethoprim-Sulfamethoxazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in pet rats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.