Reptile · Python regius · typical adult weight 1.00–2.00 kg
Trimethoprim is dosed at 15–25 mg/kg PO q24-48h in ball pythons, per Mader's Table 127.1, corpus p.1404 (printed 1194); Plumb's Sulfa-/Trimethoprim REPTILES, corpus p.1223, incl. 'may consider giving dose every other day after the second dose' — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Trimethoprim is used in ball pythons for Bacterial infections. Routes documented in ball pythons: PO. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Trimethoprim in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tribrissen
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 15–25 mg/kg | q24-48h | 7-14 days | Bacterial infections | Weak | Mader's Table 127.1, corpus p.1404 (printed 1194); Plumb's Sulfa-/Trimethoprim REPTILES, corpus p.1223, incl. 'may consider giving dose every other day after the second dose' — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 25 | PO | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.305 | 25 mg/kg p.o. q24h for 7 days for coccidiosis. |
| 10–30 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.1 | 10-30 mg/kg PO q24h99 Most species/maintain hydration |
| 30 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 30 mg/kg PO q24h × 14 days, then 1-3 ×/wk × 3-6 mo59 Most species/cryptosporidia; can reduce shedding but does not clear infection |
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These ranges are per kg. Enter your ball python's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits dihydrofolate reductase (DHFR) in folate synthesis pathway. Synergistic bactericidal activity when combined with sulfonamides.
Almost always used in combination with a sulfonamide. Folate supplementation recommended in cats and during pregnancy. KCS risk in dogs.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Trimethoprim dose range in ball pythons, with cited source references: PO 15–25 mg/kg q24-48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Trimethoprim in ball pythons: PO.
Cited course lengths for Trimethoprim in ball pythons include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Trimethoprim is indicated in ball pythons for: Bacterial infections.
These are general warnings for Trimethoprim across species; consult the ball python dosing table above for species-specific guidance. Almost always used in combination with a sulfonamide. Folate supplementation recommended in cats and during pregnancy. KCS risk in dogs.
Why a species-specific page? Trimethoprim pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 30 |
| IM |
| Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 |
| 30 mg/kg IM q24h × 2 days, then 15 mg/kg IM q48h × 10-28 days340 Most species/coccidia |
| 15 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 30 mg/kg IM q24h × 2 days, then 15 mg/kg IM q48h × 10-28 days340 Most species/coccidia |
| 3 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 3 mg/kg PO, SC, IM q24h52 Coccidiosis; unspecified sulfa |
| 15–20 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 15-20 mg/kg IM q48h52 Chronic diarrhea52 |
| 15 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.1 | 15 mg/kg PO q24h52 Chronic diarrhea |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.