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Trimethoprim for Ball Python

Reptile · Python regius · typical adult weight 1.00–2.00 kg

Trimethoprim is used in ball python for Bacterial infections. Routes documented in ball python: PO. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Trimethoprim in ball python, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Tribrissen

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO15–25 mg/kgq24-48h7-14 daysBacterial infectionsWeakCarpenter's Exotic Animal Formulary, 6th Ed

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Mechanism of action

Inhibits dihydrofolate reductase (DHFR) in folate synthesis pathway. Synergistic bactericidal activity when combined with sulfonamides.

Side effects & warnings

Almost always used in combination with a sulfonamide. Folate supplementation recommended in cats and during pregnancy. KCS risk in dogs.

Species-specific contraindications and adverse-reaction reports for ball python may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with ball python dosing

Trimethoprim dosing in other species

Why a species-specific page? Trimethoprim pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball python — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.