Cat · Felis catus · typical adult weight 2.50–7.00 kg
Warfarin is dosed at 0.06–0.09 mg/kg PO q24h in cats, per Papich MG. Saunders Handbook of Veterinary Drugs, Warfarin Sodium, printed p.848-849 - "Initial doses in cats have ranged from 0.06-0.09 mg/kg (0.25-0.5 mg/cat/day)" with the dosage table at printed p.849 giving "Cats - Start with 0.25-0.5 mg/cat/day". WARN - Plumb's 10th ed printed p.1317-1318 prints NO feline warfarin dose and states "Use in cats is not recommended" and "an increased mortality rate and a high rate of significant adverse events, including fatal hemorrhage".. Warfarin is used in cats for Arterial thromboembolism prevention. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Warfarin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Coumadin, Jantoven
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.06–0.09 mg/kg | q24h | Long-term; close monitoring essential | Arterial thromboembolism prevention | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, Warfarin Sodium, printed p.848-849 - "Initial doses in cats have ranged from 0.06-0.09 mg/kg (0.25-0.5 mg/cat/day)" with the dosage table at printed p.849 giving "Cats - Start with 0.25-0.5 mg/cat/day". WARN - Plumb's 10th ed printed p.1317-1318 prints NO feline warfarin dose and states "Use in cats is not recommended" and "an increased mortality rate and a high rate of significant adverse events, including fatal hemorrhage". |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 0.25–0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.877 | • Start with 0.25-0.5 mg/cat/day and adjust dose based on bleeding time assessment. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits vitamin K epoxide reductase, blocking synthesis of vitamin K-dependent clotting factors (II, VII, IX, X).
Narrow therapeutic index. Frequent PT/INR monitoring required. Numerous drug and dietary interactions. Hemorrhage is the main risk.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Warfarin dose range in cats, with cited source references: PO 0.06–0.09 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Warfarin in cats: PO.
Cited course lengths for Warfarin in cats include: Long-term; close monitoring essential. Duration depends on the indication — match it to the specific dose rule in the table above.
Warfarin is indicated in cats for: Arterial thromboembolism prevention.
These are general warnings for Warfarin across species; consult the cat dosing table above for species-specific guidance. Narrow therapeutic index. Frequent PT/INR monitoring required. Numerous drug and dietary interactions. Hemorrhage is the main risk.
Why a species-specific page? Warfarin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.