GI Ulceration in Rabbits
Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg
4 cited drugs treat GI Ulceration in rabbits: Cimetidine, Famotidine, Omeprazole, Sucralfate.
Erosive disease of the gastric or duodenal mucosa, often precipitated by NSAID exposure, mast-cell tumour histamine release, or stress in equines. Proton-pump inhibitors and H2 blockers reduce acid secretion; sucralfate provides mucosal protection.
The overview above describes GI Ulceration across species; the citations below are the ExoticRx dose rules scoped to rabbits — a reference list, not new species-specific clinical guidance.
Cimetidine(Tagamet)
Gastrointestinal| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5–10 mg/kg | q6-12h | As needed | Gastric acid reduction | Weak | Carpenter's Exotic Animal Formulary, 6th Ed, Table 10.10 'Miscellaneous Agents Used in Rabbits' -- 'Cimetidine 5-10 mg/kg PO, SC, IM, IV q6-12h; Gastric and duodenal ulcers' — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits).Compilation only — we have not located an independent source that prints this figure. |
Famotidine(Pepcid)
Gastrointestinal| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q12-24h | As needed | Gastric ulceration | Extrapolated | Fiorello CV. Personal communication; 2011.; Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.499, Famotidine monograph spanning p.499-500. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.18 (Treatments Used in the Management of Rabbit Gastrointestinal Syndrome (RGIS).a).Compilation only — we have not located an independent source that prints this figure. |
Omeprazole(Prilosec, GastroGard)
Gastrointestinal| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 20 mg/kg | q12h | 7-14 days | Suspected gastric ulceration | Extrapolated | Carpenter's Exotic Animal Formulary, 6th ed (2023), rabbit table (Table 10.10): "20 mg/kg SC q12h" (ref 138, Lee M, Kallal S, Feldman M).Compilation only — we have not located an independent source that prints this figure. |
Sucralfate(Carafate)
Gastrointestinal| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 25 mg/kg | q8-12h | 7-14 days | GI ulceration | Extrapolated | Carpenter's Exotic Animal Formulary, 6th Ed, rabbit miscellaneous-agents table, p.880: 'Sucralfate 25 mg/kg PO q8-12h'. Superscript 166 = Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, Orcutt C, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed. Elsevier; 2021:620-630 (verified at carpenter refs p.917). — Carpenter's Exotic Animal Formulary 6th ed, Table 10.10 (Miscellaneous Agents Used in Rabbits).Compilation only — we have not located an independent source that prints this figure. |
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.