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Coccidiosis in Rabbits

Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg

8 cited drugs treat Coccidiosis in rabbits: Amprolium, Diclazuril, Ponazuril, Sulfadimethoxine, Sulfamethazine, Sulfaquinoxaline, Toltrazuril, Trimethoprim-Sulfamethoxazole.

Protozoal infection of the intestinal tract caused by Eimeria, Isospora, and related coccidian organisms. Significant cause of diarrhoea, weight loss, and mortality in young livestock, poultry, and reptiles in particular.

The overview above describes Coccidiosis across species; the citations below are the ExoticRx dose rules scoped to rabbits — a reference list, not new species-specific clinical guidance.

Amprolium(Corid, Amprol)

Antiparasitic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO20 mg/kgq24h for 2-4 weeks7-14 daysCoccidiosisWeakBSAVA Small Animal Formulary 10th ed, Part B - Exotic Pets, p.23 (PDF p.37), Amprolium, DOSES — LOCATOR CONVENTION 2026-08-07: 'p.23' is the PRINTED page number, confirmed by finding the drug named on it in the held copy. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712

Diclazuril(Clinacox, Vecoxan)

Antiparasitic
RouteDoseFrequencyDurationIndicationEvidenceSource
SC4 mg/kgSingle SC dose2-5 days; may repeat after 7-day restHepatic and intestinal coccidiosisModerateCarpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — located 2026-08-05 in Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a); the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Ponazuril(Marquis)

Antiparasitic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO20 mg/kgq24h2-3 days; repeat in 7 daysCoccidiosis (Eimeria)ModerateAllen KE, Little SE, Johnson EM, Hostetler J, Panciera RJ, Ewing SA. Treatment of Hepatozoon americanum infection: review of the literature and experimental evaluation of efficacy. Vet Ther. 2010;11(4):E1-E8. PMID: 21308664 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1069 (2026-08-01). — Plumb's 10th ed (held) printed p.1042, Ponazuril monograph spanning p.1041-1042; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207

Sulfadimethoxine(Albon)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO50 mg/kgonce, then 25 mg/kg PO q24h x 10-20 days10-20 daysCoccidiosis (hepatic and intestinal)ModerateCarpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Sulfamethazine(Sulmet)

Antibiotic
RouteDoseFrequencyIndicationEvidenceSource
PO100 mg/kgq24hCoccidiosisWeakGillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
RouteDoseFrequencyDurationIndicationEvidenceSource
In drinking water1 mg/mL in drinking waterContinuous in water; no interval printedNo duration printed for the 1 mg/mL row.Coccidiosis; treatmentModerateMorissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852 — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350

Toltrazuril(Baycox)

Antiparasitic
RouteDoseFrequencyIndicationEvidenceSource
PO2.5–5 mg/kgonce (single oral dose)Intestinal coccidiosisModeratePlumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) | Redrobe S, Gakos G, Elliot SC, et al. Comparison of toltrazuril and sulphadimethoxine in the treatment of intestinal coccidiosis in pet rabbits. Vet Rec. 2010;167:287-290. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852 — Plumb's 10th ed (held) printed p.1257, Toltrazuril monograph spanning p.1257-1256; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Trimethoprim-Sulfamethoxazole(Bactrim, TMS)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO15–30 mg/kgq12h7-14 daysBacterial infections, coccidiosisModeratePlumb DC. Plumb's Veterinary Drug Handbook, 9th ed., Wiley Blackwell, Ames, IA; 2018. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.845 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 10.1 (Antimicrobial Agents Used in Rabbits.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.

Coccidiosis in Rabbits: 8 Cited Drug Options | ExoticRx