Coccidiosis in Rabbits

Pocket Pet · Oryctolagus cuniculus · typical adult weight 1.00–5.00 kg

8 cited drugs treat Coccidiosis in rabbits: Amprolium, Diclazuril, Ponazuril, Sulfadimethoxine, Sulfamethazine, Sulfaquinoxaline, Toltrazuril, Trimethoprim-Sulfamethoxazole.

Protozoal infection of the intestinal tract caused by Eimeria, Isospora, and related coccidian organisms. Significant cause of diarrhoea, weight loss, and mortality in young livestock, poultry, and reptiles in particular.

The overview above describes Coccidiosis across species; the citations below are the ExoticRx dose rules scoped to rabbits — a reference list, not new species-specific clinical guidance.

Amprolium(Corid, Amprol)

Antiparasitic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	20 mg/kg	q24h for 2-4 weeks	7-14 days	Coccidiosis	Weak	BSAVA Small Animal Formulary 10th ed, Part B - Exotic Pets, p.23 (PDF p.37), Amprolium, DOSESCompilation only — we have not located an independent source that prints this figure.

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Diclazuril(Clinacox, Vecoxan)

Antiparasitic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
SC	4 mg/kg	Single SC dose	2-5 days; may repeat after 7-day rest	Hepatic and intestinal coccidiosis	Moderate	Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).Compilation only — we have not located an independent source that prints this figure.

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Ponazuril(Marquis)

Antiparasitic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	20 mg/kg	q24h	2-3 days; repeat in 7 days	Coccidiosis (Eimeria)	Moderate	Allen KE, Little SE, Johnson EM, Hostetler J, Panciera RJ, Ewing SA. Treatment of Hepatozoon americanum infection: review of the literature and experimental evaluation of efficacy. Vet Ther. 2010;11(4):E1-E8. PMID: 21308664 — Plumb's 10th ed printed p.1042, Ponazuril monograph spanning p.1041-1042.

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Sulfadimethoxine(Albon)

Antibiotic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	50 mg/kg	once, then 25 mg/kg PO q24h x 10-20 days	10-20 days	Coccidiosis (hepatic and intestinal)	Moderate	Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).Compilation only — we have not located an independent source that prints this figure.

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Sulfamethazine(Sulmet)

Antibiotic

Route	Dose	Frequency	Indication	Evidence	Source
PO	100 mg/kg	q24h	Coccidiosis	Weak	GillettCS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH, Newcomer CE, eds. The Biology of the Laboratory Rabbit, 2nd ed., Academic Press, San Diego, CA; 1994:467-472. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).Compilation only — we have not located an independent source that prints this figure.

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Sulfaquinoxaline

Antibiotic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
In drinking water	1 mg/mL in drinking water	Continuous in water; no interval printed	No duration printed for the 1 mg/mL row.	Coccidiosis; treatment	Moderate	Morissey JM, Carpenter JW. Appendix: Formulary. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852Compilation only — we have not located an independent source that prints this figure.

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Toltrazuril(Baycox)

Antiparasitic

Route	Dose	Frequency	Indication	Evidence	Source
PO	2.5–5 mg/kg	once (single oral dose)	Intestinal coccidiosis	Moderate	Plumb's Veterinary Drug Handbook, 10th ed (2023) \| Redrobe S, Gakos G, Elliot SC, et al. Comparison of toltrazuril and sulphadimethoxine in the treatment of intestinal coccidiosis in pet rabbits. Vet Rec. 2010;167:287-290. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.852 — Plumb's 10th ed printed p.1257, Toltrazuril monograph spanning p.1257-1256. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).Compilation only — we have not located an independent source that prints this figure.

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Trimethoprim-Sulfamethoxazole(Bactrim, TMS)

Antibiotic

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	15–30 mg/kg	q12h	7-14 days	Bacterial infections, coccidiosis	Moderate	Plumb DC. Plumb's Veterinary Drug Handbook, 9th ed., Wiley Blackwell, Ames, IA; 2018. — Carpenter's Exotic Animal Formulary 6th ed, Table 10.1 (Antimicrobial Agents Used in Rabbits.a). — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected.Compilation only — we have not located an independent source that prints this figure.

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All drugs cited for Coccidiosis →All drugs for Rabbits →

Other conditions in Rabbits

Pain Management Sedation General Anesthesia GI Stasis (Ileus)Bacterial Infections Dermatophytosis (Ringworm)Ectoparasites GI Ulceration

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.