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Apraclonidine Ophthalmic for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Apraclonidine Ophthalmic is used in cat for Pharmacologic testing (sympathetic denervation). Routes documented in cat: Ophthalmic. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Apraclonidine Ophthalmic in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Iopidine

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
Ophthalmic0 mg/kg1 drop each eye; observe at 20, 45 minSingle diagnostic usePharmacologic testing (sympathetic denervation)ModerateGelatt KN, Veterinary Ophthalmology, 6th Ed

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Mechanism of action

Selective alpha-2 adrenergic agonist that reduces aqueous humor production and enhances uveoscleral outflow, lowering intraocular pressure.

Side effects & warnings

Tachyphylaxis develops with chronic use — best for short-term IOP reduction. May cause conjunctival blanching. Minimal systemic absorption.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Ophthalmic drugs with cat dosing

Apraclonidine Ophthalmic dosing in other species

Why a species-specific page? Apraclonidine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.