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Brincidofovir

Tembexa

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antiviral

Routes

PO

Indications

DNA virus infectionsSevere DNA virus infections (adenovirus, CMV analog)

Mechanism of Action

Lipid conjugate of cidofovir. Converted intracellularly to cidofovir diphosphate which inhibits viral DNA polymerase. Broad dsDNA virus activity.

Side effects & warnings

GI upset (diarrhea, nausea). Less nephrotoxic than IV cidofovir. Approved for smallpox. Potential use for adenovirus, CMV. No veterinary data.

Species with Brincidofovir dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO1–2 mg/kgOnce weeklyWeakPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO1–2 mg/kgOnce weeklyWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Brincidofovir