ExoticRx · exoticrx.com/drugs/foscarnet
US brand names:Foscavir
Directly inhibits viral DNA polymerase and reverse transcriptase by blocking the pyrophosphate binding site. No need for viral kinase activation.
Highly nephrotoxic. Electrolyte disturbances (hypocalcemia, hypomagnesemia). Must pre-hydrate. Penile ulceration reported.
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