Question 1

What is Cidofovir Systemic used for?

Accepted Answer

Cidofovir Systemic is indicated for: poxvirus infections, Resistant DNA virus infections, Resistant herpesvirus.

Question 2

What routes can Cidofovir Systemic be administered by?

Accepted Answer

Available routes: IV.

Question 3

Which species have cited Cidofovir Systemic dosing data?

Accepted Answer

Cidofovir Systemic dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Cidofovir Systemic a controlled substance?

Accepted Answer

Cidofovir Systemic is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Cidofovir Systemic?

Accepted Answer

Severely nephrotoxic — must co-administer probenecid and IV hydration. Neutropenia. Ocular toxicity. Monitor renal function closely.

Question 6

What are the side effects of Cidofovir Systemic?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Cidofovir Systemic: Severely nephrotoxic — must co-administer probenecid and IV hydration. Neutropenia. Ocular toxicity. Monitor renal function closely.

Question 7

How does Cidofovir Systemic work?

Accepted Answer

Nucleotide analogue that inhibits viral DNA polymerase. Does not require viral kinase activation. Active against CMV, adenovirus, polyomavirus, poxviruses.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IV	5 mg/kg	Once weekly x 2, then q2wk	Weak	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IV	5 mg/kg	Once weekly x 2, then q2wk	Weak	Plumb's Veterinary Drug Handbook, 9th Ed

Cidofovir Systemic

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Cidofovir Systemic dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published source

Sample dosing (2 of 2 cited rules)

Upgrade for Full Details