ExoticRx · exoticrx.com/drugs/carbimazole
US brand names:Neo-Mercazole, Vidalta
Carbimazole is dosed at 1–2 mg/kg PO q24h in guinea pigs, per Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. / Mayer J, Wagner R, Taeymans O. Advanced diagnostic approaches and current management of thyroid pathologies in guinea pigs. Vet Clin North Am Exot Anim Pract. 2010;13:509-523. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.799 doi:10.1055/b-004-129947 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.7 (Miscellaneous Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Prodrug rapidly converted to methimazole, which inhibits thyroid peroxidase enzyme, blocking thyroid hormone synthesis.
Similar side effects as methimazole. Monitor CBC (agranulocytosis risk), liver enzymes, renal function. Better GI tolerance than methimazole in some cats.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Guinea Pig drugs
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A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | PO | 2.5–5 mg per cat | q8-12h then q12h maintenance (immediate-release) | Strong | JFMS 2016; Plumb's Veterinary Drug Handbook — corpus p.212 (plumb), located 2026-08-05 by exact figure+drug match (unique, drug within 70 chars). — LOCATOR CONVENTION 2026-08-07: the bare 'p.212' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.185; verified by finding the drug named there. If you are holding the book, turn to p.185. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | PO | 10–15 mg per ANIMAL (NOT mg/kg) | q24h; adjust in 5 mg steps, do not split | Weak | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.184, Carbimazole monograph spanning p.184-185; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Carbimazole monograph, printed p.184-185; the earlier note claiming no held source contained this figure was wrong and has been removed. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.